KEGG   Homo sapiens (human): 8535
Entry
8535              CDS       T01001                                 
Symbol
CBX4, NBP16, PC2
Name
(RefSeq) chromobox 4
  KO
K11452  E3 SUMO-protein ligase CBX4 [EC:2.3.2.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03083  Polycomb repressive complex
Network
nt06523  Epigenetic regulation by Polycomb complexes
  Element
N01577  Gene silencing by methylation of H3K27 and ubiquitination of H2AK119
N01585  Deubiquitination of H2AK119
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09126 Chromosome
   03083 Polycomb repressive complex
    8535 (CBX4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    8535 (CBX4)
   03036 Chromosome and associated proteins [BR:hsa03036]
    8535 (CBX4)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  UBL E3 ligases
   8535 (CBX4)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   Polycomb repressive complex (PRC) and associated proteins
    Canonical PRC1 (PRC1.2/1.4)
     8535 (CBX4)
SSDB
Motif
Pfam: Chromo CBX7_C Mtf2_C
Other DBs
NCBI-GeneID: 8535
NCBI-ProteinID: NP_003646
OMIM: 603079
HGNC: 1554
Ensembl: ENSG00000141582
UniProt: O00257 A0A0S2Z5B2
Structure
Position
17:complement(79833156..79839440)
AA seq 560 aa
MELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNR
ERQEQLMGYRKRGPKPKPLVVQVPTFARRSNVLTGLQDSSTDNRAKLDLGAQGKGQGHQY
ELNSKKHHQYQPHSKERAGKPPPPGKSGKYYYQLNSKKHHPYQPDPKMYDLQYQGGHKEA
PSPTCPDLGAKSHPPDKWAQGAGAKGYLGAVKPLAGAAGAPGKGSEKGPPNGMMPAPKEA
VTGNGIGGKMKIVKNKNKNGRIVIVMSKYMENGMQAVKIKSGEVAEGEARSPSHKKRAAD
ERHPPADRTFKKAAGAEEKKVEAPPKRREEEVSGVSDPQPQDAGSRKLSPTKEAFGEQPL
QLTTKPDLLAWDPARNTHPPSHHPHPHPHHHHHHHHHHHHAVGLNLSHVRKRCLSETHGE
REPCKKRLTARSISTPTCLGGSPAAERPADLPPAAALPQPEVILLDSDLDEPIDLRCVKT
RSEAGEPPSSLQVKPETPASAAVAVAAAAAPTTTAEKPPAEAQDEPAESLSEFKPFFGNI
IITDVTANCLTVTFKEYVTV
NT seq 1683 nt   +upstreamnt  +downstreamnt
atggagctgccagctgttggcgagcacgtcttcgcggtggagagcatcgagaagaagcgg
atccgcaagggcagagtggagtatctggtgaaatggagaggctggtcgcccaaatataac
acgtgggaaccggaggagaacatcctggaccccaggctgctgatcgccttccagaacagg
gaacggcaggagcagctgatgggatatcggaagagagggccgaagcccaaaccgctagtg
gtgcaggtgcctacctttgcccgtcgttccaatgtcctgaccggcctccaggactcctcc
actgacaaccgtgccaagctggatttgggcgcgcaggggaagggccaggggcatcagtac
gagctcaacagcaagaagcaccaccagtaccagccgcacagcaaggagcgggcgggcaag
cccccgccgccgggcaagagcggcaagtactactaccagctcaacagcaagaagcaccac
ccctaccagcccgaccccaaaatgtacgacctgcagtaccagggcggccacaaggaggcg
cccagccccacctgcccggacctgggggccaagagccacccgcccgacaagtgggcgcaa
ggtgcgggggccaaaggctacctgggggcggtgaagcccctggccggtgcggcgggtgct
ccaggcaaaggctccgagaagggcccccccaacggaatgatgccggcccccaaagaggct
gtgacgggcaacgggattgggggcaagatgaagatagtcaagaacaagaacaagaacgga
cgcatcgtgatcgtgatgagcaaatacatggagaacggcatgcaggcggtgaagatcaag
tccggcgaggtggcagagggggaggctcgctcccccagccacaagaagcgggcagccgac
gagcgccaccctcctgccgacaggacttttaaaaaggcggcgggcgcagaggagaagaag
gtggaggcgccgcccaagaggagggaggaggaggtgtccggggttagcgatccgcagccc
caggatgccggctcccgcaagctgtccccgaccaaggaggcctttggagagcagcccctg
cagctcaccaccaagcccgacctgcttgcctgggacccggcccggaacacgcacccgccc
tcacaccacccgcacccgcacccccatcaccaccaccaccaccaccaccaccaccaccac
gccgtcggcctgaatctctcccacgtgcgcaagcgctgcctctccgagacccacggcgag
cgcgagccctgcaagaagcggctgactgcgcgcagcatcagcacccccacctgcctgggg
ggcagcccagccgctgagcgcccggccgacctgccaccagccgccgccctcccgcagccc
gaggtcatcctgctagactcagacctggatgaacccatagacttgcgctgcgtcaagacg
cgcagcgaggccggggagccgcccagctccctccaggtgaagcccgagacaccggcgtcg
gcggcggtggcggtggcggcggcagcggcacccaccacgacggcggagaagcctccagcc
gaggcccaggacgaacctgcagagtcgctgagcgagttcaagcccttctttgggaatata
attatcaccgacgtcaccgcgaactgcctcaccgttactttcaaggagtacgtgacggtg
tag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (3)   
   KEGG NETWORK (3)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (23)   
   RefSeq(nuc) (3)   
   GenBank (10)   
   EMBL (10)   
3D Structure (3)   
   PDB (3)   
Protein domain (3)   
   Pfam (3)   
All databases (68)   

Download RDF
DBGET integrated database retrieval system